Low-dose radiation cancer susceptibility models

Low-dose radiation cancer susceptibility models

the biological effects of low-dose radiation exposure are increasingly better understood, continued research is needed to develop better individual risk-based models. Human population exposures to low doses of ionizing radiation (defined by the US Department of Energy as less than 10 rem or 0.1 Sv) are increasing due to occupational exposures of nuclear plant workers, waste managers and medical...

Low-dose or low-dose-rate ionizing radiation–induced bioeffects in animal models

Animal experimental studies indicate that acute or chronic low-dose ionizing radiation (LDIR) (≤100 mSv) or low-dose-rate ionizing radiation (LDRIR) (<6 mSv/h) exposures may be harmful. It induces genetic and epigenetic changes and is associated with a range of physiological disturbances that includes altered immune system, abnormal brain development with resultant cognitive impairment, catarac...

New insight into cancer risks from radiation exposure of low dose and low dose rate

For example, the Chernobyl accident caused the deposition of radioisotopes over wide areas of the Northern Hemisphere, in particular in Europe ( Atlas of Caesium Deposition on Europe after the Chernobyl Accident, 1998), followed by protracted chronic exposure of some millions of people to external and internal radiation. You can see the map of radioactive contamination of Europe after the Chern...

Low-dose extrapolation of radiation-related cancer risk.

Treatment of Cancer and Inflammation With Low-Dose Ionizing Radiation

There is considerable evidence from experimental studies in animals, as well as from clinical reports, that low-dose radiation hormesis is effective for the treatment of cancer and ulcerative colitis. In this study, we present 3 case reports that support the clinical efficacy of low-dose radiation hormesis in patients with these diseases. First, a patient with prostate cancer who had undergone ...